3. Does Celebrex interact with alcohol? When Celebrex and alcohol are taken together, they could negatively affect the stomach or liver. It is essential to avoid alcohol while taking the medication. Increased Risk of Stomach Bleeding & Ulcers: Celebrex, like other NSAIDs, can irritate the stomach lining. Alcohol also irritates the stomach and can increase stomach acid production. Together, they may raise the risk of gastritis, ulcers, or gastrointestinal bleeding. Liver Toxicity (Less Common but Possible): Celebrex is metabolized by the liver, and excessive alcohol use can strain liver function. While Celebrex alone rarely causes liver damage, heavy alcohol use could increase this risk. Dizziness or Drowsiness (Mild Effect): Some people report mild drowsiness with Celebrex, which could be worsened by alcohol. https://buynetmeds.com/product/celebrex-200mg/