The Cutting-Edge of Targeted Protein Degradation: PROTACs, Linkers, and Molecular Glues
n recent years, the field of drug discovery has witnessed a transformative shift towards targeted protein degradation, a strategy that offers new avenues for treating diseases, particularly cancers and other conditions driven by aberrant protein activity. Among the forefront of this innovative approach are Proteolysis Targeting Chimeras (PROTAC), their essential linkers, and the emerging...
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