The vector purification market is estimated to be valued at USD 336 Mn in 2024 and is expected to reach USD 1,300 Mn by 2031, growing at a compound annual growth rate (CAGR) of 21.3% from 2024 to 2031.

Vector purification involves various techniques and processes used to extract gene transfer vectors including viral vectors from mixtures and cell and tissue cultures. These extracted vectors are further used for various gene transfer therapies like gene therapy and cell therapy. The demand for gene and cell therapies is growing rapidly owing to increasing prevalence of diseases like cancer, genetic disorders. Viral vectors like lentivirus, retrovirus, adenovirus are commonly used as vectors to deliver therapeutic genes into target cells without integrating into the host genome. The process of vector purification helps in removing contaminants and isolation of high titre and pure viral vectors required for effective and safe gene delivery.

Key players operating in the Vector Purification market are Thermo Fisher Scientific, Merck KGaA, Danaher, Sartorius AG, General Electric, BD, Lonza, autoMACS, Miltenyi Biotec, and PlasmidFactory.

The growing demand for cell and gene therapies is a major factor driving the growth of the Vector Purification Market. Cell and gene therapies require high quality and high titre viral vectors for effective delivery of therapeutic genes without any safety issues. According to reports, currently there are more than 2000 ongoing clinical trials on various cell and gene therapies.

Technological advancements in vector purification methods like affinity chromatography, precipitation, ultracentrifugation, and size-exclusion chromatography have helped in developing efficient and robust processes extracting high titre and pure viral vectors from cell culture supernatants. This has boosted the production capacities of various vector manufacturing facilities.

Market Trends
- Continuous processing technologies: Development of continuous processing techniques for vector purification like continuous chromatographic procedures help in reducing processing time and improving yields.

- Automation of purification: Integration of automation and robotics in vector manufacturing has increased efficiencies and productivity of purification processes helping meet the increasing demand.

Market Opportunities
- Customized purification services: Opportunity for Contract Manufacturing Organizations to offer customized purification services as per individual vector requirements.

- Development of new vectors: Scope for development and commercialization of new viral vector platforms like Adeno-Associated Virus vectors for wider applications in gene and cell therapies.
Impact of COVID-19 on Vector Purification Market growth
The outbreak of COVID-19 pandemic has adversely impacted the vector purification market growth. During the initial phase of pandemic, restriction on transportation and lockdown imposed by governments globally disrupted the supply chain and logistics. This affected the procurement of raw materials required for vector purification process. Moreover, research activities requiring vector purification witnessed a decline due to closure of research laboratories. Additionally, diversion of resources towards development of vaccine and therapeutics for COVID-19 treatment also hampered the market.

However, post pandemic the market is expected to rebound at a steady pace. With resumption of research activities and relaxation in lockdown measures, demand for vector purification is likely to rise significantly. The ongoing clinical trials for development of various gene and cell therapies will necessitate vector purification procedures. Furthermore, increasing R&D towards development of viral vectors for vaccine delivery against COVID-19 and other diseases will augment the demand. Market players are also expanding their production facilities to cope up with the growing requirements.

Geographical concentration of Vector Purification Market in terms of value
North America represents the most lucrative region for vector purification market in terms of value. Presence of prominent players, advanced research infrastructure and increasing funding for gene therapy research drives the regional market growth. The United States accounts for majority of share owing to large number of ongoing gene and cell therapy clinical trials. Asia Pacific is poised to be the fastest growing region during the forecast period due to rising genetic and biopharmaceutical industry, improving healthcare infrastructure and initiatives to promote indigenous production of viral vectors in countries like China and India.

Fastest growing region for Vector Purification Market
Asia Pacific region is expected to witness the fastest growth in the vector purification market over the forthcoming years. Factors such as rising healthcare expenditure, increasing incidence of chronic diseases, growing geriatric population susceptible to genetic disorders, and improving research capabilities are favoring the market expansion. In addition, presence of large patient pool, low-cost skilled labor and lenient regulatory environment make Asia Pacific an ideal destination for outsourcing of vector purification processes. Countries like China, India, Japan and South Korea are anticipated to be the major revenue generators in the region.

Get more insights on: Vector Purification Market

Get this Report in Japanese Language: ベクター精製市場

Get this Report in Korean Language: 벡터 정화 시장

About Author:

Ravina Pandya, Content Writer, has a strong foothold in the market research industry. She specializes in writing well-researched articles from different industries, including food and beverages, information and technology, healthcare, chemical and materials, etc. (https://www.linkedin.com/in/ravina-pandya-1a3984191)